DBNL

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DBNL RNA expression is significantly associated with the protein abundance of many other proteins, with 7,965 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DBNL-associated proteins across cancer lineages are NUDCD3, PURB, and YKT6. Each is linked with DBNL in more than 6 cancer types. Because this analysis shows association rather than direction, both DBNL-to-partner and partner-to-DBNL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DBNL versus NUDCD3 in LUAD, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DBNL→partner) and Y-score (partner→DBNL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADNUDCD3 →+0.346+0.428<.001<.00137
HNSCPURB →+0.321+0.574<.001.00725
OVYKT6 →+0.247+0.395<.001.00325
GBMPTPN12 →+0.278+0.227.001.00434
UCECNFXL1 →-0.330-0.478<.001.00233
PDACTRAPPC11_S71 →-0.403-0.251<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,965 associations by consensus.

DBNL vs NUDCD3 — LUAD

Per-sample scatter of DBNL vs NUDCD3 in LUAD (Pearson r = 0.66).

Explore this scatter interactively →

Exploration