DBNL

Across TCGA cell cohorts, DBNL RNA expression is significantly associated with the go_rna of many other GO terms, with 5,090 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DBNL-associated GO terms across cancer lineages are 2-oxoglutarate decarboxylation to succinyl-CoA, Cytosolic transport, and Negative regulation of calcium ion export across plasma membrane. Each is linked with DBNL in more than 14 cancer types. Because this analysis shows association rather than direction, both DBNL-to-partner and partner-to-DBNL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 2-oxoglutarate decarboxylation to succinyl-CoA grouped by DBNL-low versus DBNL-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DBNL→partner) and Y-score (partner→DBNL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	2-oxoglutarate decarboxylation to succinyl-CoA →	+0.115	+0.686	.004	.001	3	15
BREAST	Cytosolic transport →	+0.071	+1.205	<.001	<.001	3	14
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.069	+0.793	.002	.008	3	14
LUNG_NSCLC_LUSC	Latent virus replication →	+0.192	+0.792	.003	.006	3	13
LUNG_NSCLC_LUSC	Release from viral latency →	+0.192	+0.792	.003	.006	3	13
LUNG_NSCLC_LUSC	Protein-containing complex disassembly →	+0.070	+0.926	.005	<.001	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,090 associations by consensus.

2-oxoglutarate decarboxylation to succinyl-CoA by DBNL expression — KIDNEY

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