DBIP2

Across TCGA patient cohorts, DBIP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,962 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DBIP2-associated GO terms across cancer lineages are Positive regulation of DNA repair, Positive regulation of DNA metabolic process, and Regulation of double-strand break repair. Each is linked with DBIP2 in more than 18 cancer types. Because this analysis shows association rather than direction, both DBIP2-to-partner and partner-to-DBIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by DBIP2-low versus DBIP2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DBIP2→partner) and Y-score (partner→DBIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA repair →	+0.039	+0.132	<.001	<.001	3	19
STAD	Positive regulation of DNA metabolic process →	+0.042	+0.119	<.001	.001	3	17
STAD	Regulation of double-strand break repair →	+0.040	+0.128	<.001	<.001	3	17
STAD	Telomere maintenance →	+0.052	+0.206	<.001	.002	3	17
STAD	Regulation of transcription elongation by RNA polymerase II →	+0.058	+0.147	<.001	<.001	3	16
THYM	Regulation of mitotic sister chromatid segregation →	+0.064	+0.325	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,962 associations by consensus.

Positive regulation of DNA repair by DBIP2 expression — STAD

Explore this box plot interactively →