DBI

Across TCGA patient cohorts, DBI protein abundance is significantly associated with the RNA expression of many other genes, with 9,356 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DBI-associated genes across cancer lineages are LINC02038, DSE, and ATP13A4. Each is linked with DBI in more than 3 cancer types. Because this analysis shows association rather than direction, both DBI-to-partner and partner-to-DBI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DBI versus LINC02038 in PDAC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DBI→partner) and Y-score (partner→DBI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	LINC02038 →	+0.754	+0.213	<.001	<.001	3	4
HNSC	DSE →	-0.696	-0.386	<.001	<.001	3	4
GBM	ATP13A4 →	+1.126	+0.463	<.001	<.001	3	4
LSCC	LOXL2 →	-1.248	-0.417	<.001	<.001	3	4
GBM	PRSS23 →	-1.289	-0.640	<.001	<.001	3	4
GBM	ATP13A4-AS1 →	+1.458	+0.607	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,356 associations by consensus.

DBI vs LINC02038 — PDAC

Explore this scatter interactively →