DBI

Across TCGA cell cohorts, DBI RNA expression is significantly associated with the go_rna of many other GO terms, with 4,232 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DBI-associated GO terms across cancer lineages are Secondary alcohol biosynthetic process, Zymosterol metabolic process, and Zymosterol biosynthetic process. Each is linked with DBI in more than 12 cancer types. Because this analysis shows association rather than direction, both DBI-to-partner and partner-to-DBI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Secondary alcohol biosynthetic process grouped by DBI-low versus DBI-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DBI→partner) and Y-score (partner→DBI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Secondary alcohol biosynthetic process →	+0.146	+0.791	<.001	<.001	3	13
SOFT_TISSUE	Zymosterol metabolic process →	+0.147	+0.700	<.001	<.001	3	13
SOFT_TISSUE	Zymosterol biosynthetic process →	+0.147	+0.700	<.001	<.001	3	13
BONE	Steroid biosynthetic process →	+0.115	+1.331	.001	.001	3	13
SOFT_TISSUE	Cholesterol biosynthetic process →	+0.146	+0.791	<.001	<.001	3	13
BREAST	Farnesyl diphosphate metabolic process →	+0.185	+1.285	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,232 associations by consensus.

Secondary alcohol biosynthetic process by DBI expression — SOFT_TISSUE

Explore this box plot interactively →