DAZL

Across TCGA patient cohorts, DAZL RNA expression is significantly associated with the go_rna of many other GO terms, with 7,065 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DAZL-associated GO terms across cancer lineages are T cell homeostasis, Regulation of lymphocyte differentiation, and Alpha-beta T cell activation. Each is linked with DAZL in more than 21 cancer types. Because this analysis shows association rather than direction, both DAZL-to-partner and partner-to-DAZL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T cell homeostasis grouped by DAZL-low versus DAZL-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAZL→partner) and Y-score (partner→DAZL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	T cell homeostasis →	+0.081	+0.424	<.001	<.001	3	22
STAD	Regulation of lymphocyte differentiation →	+0.065	+0.379	<.001	<.001	3	21
STAD	Alpha-beta T cell activation →	+0.073	+0.411	<.001	<.001	3	21
STAD	Positive regulation of alpha-beta T cell activation →	+0.068	+0.369	<.001	<.001	3	21
STAD	Antigen receptor-mediated signaling pathway →	+0.079	+0.380	<.001	<.001	3	21
STAD	Regulation of leukocyte proliferation →	+0.073	+0.479	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,065 associations by consensus.

T cell homeostasis by DAZL expression — STAD

Explore this box plot interactively →