DAZL

Across TCGA patient cohorts, DAZL protein abundance is significantly associated with the RNA expression of many other genes, with 2,540 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DAZL-associated genes across cancer lineages are PPP1R13L, NUP210, and SPOCK2. Each is linked with DAZL in more than 3 cancer types. Because this analysis shows association rather than direction, both DAZL-to-partner and partner-to-DAZL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DAZL versus PPP1R13L in OV, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAZL→partner) and Y-score (partner→DAZL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PPP1R13L →	+1.580	+0.943	<.001	<.001	3	4
BRCA	NUP210 →	-1.068	-0.828	.003	.001	3	2
PDAC	SPOCK2 →	-0.561	-0.518	.002	.002	3	2
GBM	RAB22A →	+0.310	+0.454	.003	.009	3	2
UCEC	MED12L →	-0.733	-0.400	.009	.009	3	2
HNSC	GPC3 →	-1.568	-0.858	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,540 associations by consensus.

DAZL vs PPP1R13L — OV

Explore this scatter interactively →