Across TCGA cell cohorts, DAXX RNA expression is significantly associated with the RNA expression of many other genes, with 11,073 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DAXX-associated genes across cancer lineages are DHX16, EHMT2, and PRRC2A. Each is linked with DAXX in more than 18 cancer types. Because this analysis shows association rather than direction, both DAXX-to-partner and partner-to-DAXX results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAXX→partner) and Y-score (partner→DAXX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	DHX16 →	+1.257	+1.207	<.001	<.001	3	19
KIDNEY	EHMT2 →	+1.086	+0.679	<.001	<.001	3	18
URINARY_TRACT	PRRC2A →	+1.336	+1.149	<.001	<.001	3	18
OESOPHAGUS	ABCF1 →	+0.987	+0.730	<.001	<.001	2	19
URINARY_TRACT	GNL1 →	+1.264	+0.986	<.001	<.001	3	18
OESOPHAGUS	TRIM39 →	+1.079	+0.983	<.001	<.001	2	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,073 associations by consensus.

Exploration

DAXX survival (RNA) · tumor vs normal (RNA) · all DAXX data types