DAXX

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DAXX RNA expression is significantly associated with the go_rna of many other GO terms, with 4,222 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DAXX-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, Nucleosome disassembly, and Protein localization to chromatin. Each is linked with DAXX in more than 14 cancer types. Because this analysis shows association rather than direction, both DAXX-to-partner and partner-to-DAXX results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAXX→partner) and Y-score (partner→DAXX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONENegative regulation of RNA export from nucleus →+0.169+0.860<.001<.001315
URINARY_TRACTNucleosome disassembly →+0.139+0.833<.001.003215
BONEProtein localization to chromatin →+0.114+0.558<.001<.001314
PANCREASTranscription initiation-coupled chromatin remodeling →+0.081+0.828<.001<.001314
BONEMeiotic chromosome condensation →+0.162+0.584.002.004313
BONEChromosome condensation →+0.184+0.844.006<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,222 associations by consensus.

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