DAPL1

Across TCGA patient cohorts, DAPL1 protein abundance is significantly associated with the protein abundance of many other proteins, with 6,174 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DAPL1-associated proteins across cancer lineages are CYP2S1, SIPA1, and VAV2. Each is linked with DAPL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DAPL1-to-partner and partner-to-DAPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DAPL1 versus CYP2S1 in LSCC, with a Pearson correlation of 0.51.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DAPL1→partner) and Y-score (partner→DAPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CYP2S1 →	+0.816	+1.487	<.001	<.001	3	3
OV	SIPA1 →	-0.295	-1.031	<.001	<.001	3	3
BRCA	VAV2 →	-0.793	-1.993	<.001	.006	3	3
LSCC	DLG1_S687 →	+0.954	+1.915	<.001	<.001	3	3
OV	ELMO2 →	-0.336	-1.355	<.001	.001	3	3
LSCC	GRHL3_S215 →	+1.689	+2.022	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,174 associations by consensus.

DAPL1 vs CYP2S1 — LSCC

Explore this scatter interactively →