DAPK2

Across TCGA cell cohorts, DAPK2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DAPK2-associated genes across cancer lineages are TEX51, MAGEB4, and CRISP1. Each is linked with DAPK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DAPK2-to-partner and partner-to-DAPK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX51 grouped by DAPK2-low versus DAPK2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAPK2→partner) and Y-score (partner→DAPK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TEX51 →	+0.026	+5.643	<.001	.002	3	1
LARGE_INTESTINE	MAGEB4 →	+0.022	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CRISP1 →	+0.014	+4.415	<.001	.007	3	1
LARGE_INTESTINE	STRA8 →	+0.161	+4.415	<.001	.007	3	1
LARGE_INTESTINE	ZNF804B →	+0.016	+4.415	<.001	.007	3	1
LARGE_INTESTINE	DAZ2 →	+0.252	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

TEX51 by DAPK2 expression — BLOOD_Lymphoma

Explore this box plot interactively →