DAPK1-IT1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DAPK1-IT1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated DAPK1-IT1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher DAPK1-IT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DAPK1-IT1 expression acts as an unfavorable survival marker, although some lineages such as STAD and BLCA show a favorable association.

ACC, MESO, and BRCA are the cancer types where DAPK1-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCOSQuartileAll0.7320.914<.00151view →
MESOOSTertileIII,IV0.3910.642.00150view →
BRCADFSTertileAll0.5701.000.03336view →
THYMDFSTertileIII,IV0.2240.879.00236view →
COADOSTertileIII,IV0.2090.591.01627view →
THCADFSTertileIII,IV0.5330.811.01927view →
READOSTertileIV0.2890.899<.00118view →
SARCDFSTertileAll0.2370.369.02315view →
STADDFSTertileIII,IV0.6670.448.01513view →
LUSCOSTertileII,III,IV0.2770.455.03213view →
BLCAOSTertileII,III,IV0.7850.680.02112view →
PCPGDFSTertileAll0.9760.697.02512view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

DAPK1-IT1–ACC (OS)

Kaplan–Meier survival curve for DAPK1-IT1 RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration