DAPK1-IT1

Across TCGA pan-cancer cohorts, DAPK1-IT1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of DAPK1-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where DAPK1-IT1 RNA is repressed in tumor relative to normal tissue. In most cancer types DAPK1-IT1 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

LUSC, THCA, and BRCA are the cancer types where DAPK1-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DAPK1-IT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.072	.012	2	view →
THCA	Female	II,III,IV	−0.060	.033	2	view →
BRCA	All	III,IV	−0.039	.014	2	view →
CHOL	All	All	+0.102	.032	1	view →
KICH	All	All	−0.049	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

DAPK1-IT1–LUSC

Open the LUSC breakdown →