DAP3

Across TCGA cell cohorts, DAP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,513 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DAP3-associated GO terms across cancer lineages are Positive regulation of rRNA processing, Nuclear pore complex assembly, and Pseudouridine synthesis. Each is linked with DAP3 in more than 12 cancer types. Because this analysis shows association rather than direction, both DAP3-to-partner and partner-to-DAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of rRNA processing grouped by DAP3-low versus DAP3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAP3→partner) and Y-score (partner→DAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of rRNA processing →	+0.110	+0.460	<.001	.002	2	13
SOFT_TISSUE	Nuclear pore complex assembly →	+0.134	+0.435	<.001	.005	3	10
LARGE_INTESTINE	Pseudouridine synthesis →	+0.070	+0.488	<.001	<.001	3	10
BLOOD_Lymphoma	Mitochondrial large ribosomal subunit assembly →	+0.113	+0.593	<.001	.001	3	10
SOFT_TISSUE	Nuclear pore organization →	+0.142	+0.396	<.001	.006	3	10
SOFT_TISSUE	Mitochondrial RNA metabolic process →	+0.089	+0.461	<.001	.004	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,513 associations by consensus.

Positive regulation of rRNA processing by DAP3 expression — SOFT_TISSUE

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