DACH1

Across TCGA patient cohorts, DACH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,209 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DACH1-associated proteins across cancer lineages are MYEF2, LAMB2, and UPP1. Each is linked with DACH1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DACH1-to-partner and partner-to-DACH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DACH1 versus MYEF2 in HNSC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DACH1→partner) and Y-score (partner→DACH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MYEF2 →	+0.724	+0.816	<.001	<.001	3	6
HNSC	LAMB2 →	+0.596	+0.653	<.001	.001	3	6
HNSC	UPP1 →	-0.988	-0.859	<.001	.001	3	6
HNSC	DDAH2 →	+0.498	+1.004	<.001	<.001	3	6
HNSC	SPAG9_S332 →	-0.807	-0.969	<.001	.002	3	5
BRCA	TCEAL1 →	+0.765	+2.116	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,209 associations by consensus.

DACH1 vs MYEF2 — HNSC

Explore this scatter interactively →