DAB2

Across TCGA pan-cancer cohorts, DAB2 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated DAB2 data layer compared with 17 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DAB2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated DAB2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, LUAD, and GBM are the cancer types where DAB2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	1.000	0.888	.003	44	view →
LUAD	DFS	Tertile	All	1.000	0.595	.034	2	view →
GBM	OS	Quartile	All	0.201	0.564	.027	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

DAB2–CCRCC (OS)

Open the CCRCC breakdown →