DAB2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DAB2 protein abundance is significantly associated with the RNA expression of many other genes, with 20,374 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DAB2-associated genes across cancer lineages are CD33, PIK3CG, and CXCL12. Each is linked with DAB2 in more than 8 cancer types. Because this analysis shows association rather than direction, both DAB2-to-partner and partner-to-DAB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DAB2 versus CD33 in GBM, with a Pearson correlation of 0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAB2→partner) and Y-score (partner→DAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCD33 →+0.875+0.817<.001<.00139
LSCCPIK3CG →+0.844+0.394<.001<.00139
OVCXCL12 →+1.806+0.500<.001<.00139
OVBST1 →+0.798+0.304.002<.00139
GBMIL10RA →+1.223+0.803<.001<.00139
GBMST8SIA4 →+1.005+0.856<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,374 associations by consensus.

DAB2 vs CD33 — GBM

Per-sample scatter of DAB2 vs CD33 in GBM (Pearson r = 0.77).

Explore this scatter interactively →

Exploration