DAB2

Across TCGA cell cohorts, DAB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,431 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DAB2-associated GO terms across cancer lineages are Positive regulation of mineralocorticoid secretion, Positive regulation of aldosterone secretion, and Positive regulation of aldosterone biosynthetic process. Each is linked with DAB2 in more than 16 cancer types. Because this analysis shows association rather than direction, both DAB2-to-partner and partner-to-DAB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mineralocorticoid secretion grouped by DAB2-low versus DAB2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAB2→partner) and Y-score (partner→DAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of mineralocorticoid secretion →	+1.329	+2.869	<.001	<.001	3	17
SOFT_TISSUE	Positive regulation of aldosterone secretion →	+1.329	+2.869	<.001	<.001	3	17
URINARY_TRACT	Positive regulation of aldosterone biosynthetic process →	+1.739	+3.174	<.001	<.001	3	17
BREAST	Regulation of mineralocorticoid secretion →	+1.321	+2.744	<.001	<.001	3	16
BREAST	Regulation of aldosterone secretion →	+1.321	+2.744	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.060	+1.967	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,431 associations by consensus.

Positive regulation of mineralocorticoid secretion by DAB2 expression — SOFT_TISSUE

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