DAB1

Across TCGA patient cohorts, DAB1 protein abundance is significantly associated with the RNA expression of many other genes, with 520 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DAB1-associated genes across cancer lineages are RRP8, LGALS12, and CASQ1. Each is linked with DAB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DAB1-to-partner and partner-to-DAB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DAB1 versus RRP8 in PDAC, with a Pearson correlation of -0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAB1→partner) and Y-score (partner→DAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RRP8 →	-0.400	-0.660	.006	.004	3	1
PDAC	LGALS12 →	-0.557	-0.490	.001	.002	3	1
PDAC	CASQ1 →	-0.317	-0.458	<.001	.005	3	1
PDAC	C1orf131 →	-0.414	-0.577	.008	.002	3	1
PDAC	ABT1 →	-0.383	-0.555	<.001	<.001	3	1
PDAC	TEKT4 →	+0.178	+0.759	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 520 associations by consensus.

DAB1 vs RRP8 — PDAC

Explore this scatter interactively →