DAB1

Across TCGA pan-cancer cohorts, DAB1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated DAB1 data layer compared with 9 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher DAB1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DAB1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and SKCM show a favorable association.

OV, PAAD, and SKCM are the cancer types where DAB1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Quartile	All	0.743	0.903	<.001	58	view →
PAAD	DFS	Quartile	All	0.593	0.355	.002	46	view →
SKCM	OS	Tertile	All	0.416	0.291	<.001	41	view →
KIRP	OS	Tertile	All	0.427	0.760	<.001	38	view →
UCEC	DFS	Tertile	All	0.566	0.695	.003	34	view →
THYM	OS	Median	All	0.914	1.000	.005	31	view →
ACC	DFS	Quartile	All	0.690	0.331	.004	30	view →
UVM	OS	Tertile	III,IV	0.353	1.000	.022	26	view →
COAD	OS	Median	IV	0.865	0.432	.007	21	view →
KICH	DFS	Tertile	III,IV	0.279	0.864	.007	20	view →
READ	OS	Median	All	0.778	0.546	.003	16	view →
LIHC	OS	Tertile	All	0.742	0.412	<.001	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

DAB1–OV (OS)

Open the OV breakdown →