DAB1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DAB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,754 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DAB1-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, Regulation of RNA splicing, and Epigenetic regulation of gene expression. Each is linked with DAB1 in more than 8 cancer types. Because this analysis shows association rather than direction, both DAB1-to-partner and partner-to-DAB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process grouped by DAB1-low versus DAB1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAB1→partner) and Y-score (partner→DAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONENuclear-transcribed mRNA catabolic process →+0.067+2.689<.001.00138
BLOOD_LeukemiaRegulation of RNA splicing →+0.029+0.615.003.00529
BONEEpigenetic regulation of gene expression →+0.069+3.018.003.00237
BONEGlucosylceramide metabolic process →-0.232-2.425.001<.00136
BONERegulation of cytoplasmic translation →+0.104+2.833<.001<.00136
BONERegulation of glucose mediated signaling pathway →+0.105+2.765<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,754 associations by consensus.

Nuclear-transcribed mRNA catabolic process by DAB1 expression — BONE

Box plot of Nuclear-transcribed mRNA catabolic process in DAB1-low vs DAB1-high samples in BONE.

Explore this box plot interactively →

Exploration