DAAM2

Across TCGA patient cohorts, DAAM2 mutation is significantly associated with the RNA expression of many other genes, with 3,710 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DAAM2-associated genes across cancer lineages are LINC02002, OIP5, and HAUS2. Each is linked with DAAM2 in more than 3 cancer types. Because this analysis shows association rather than direction, both DAAM2-to-partner and partner-to-DAAM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02002 grouped by DAAM2-low versus DAAM2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAAM2→partner) and Y-score (partner→DAAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LINC02002 →	+0.077	+2.738	.002	.008	3	4
COAD	OIP5 →	+0.478	+1.887	.001	.001	3	4
UCEC	HAUS2 →	+0.378	+1.540	.001	.001	3	4
UCEC	POLR2A →	+0.407	+1.880	.007	.004	3	4
COAD	SLF1 →	+0.295	+2.512	.004	<.001	3	4
COAD	PRSS23 →	-0.743	-3.893	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,710 associations by consensus.

LINC02002 by DAAM2 expression — BRCA

Explore this box plot interactively →