CYTIP

Across TCGA pan-cancer cohorts, CYTIP Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CYTIP data layer compared with 27 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CYTIP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CYTIP expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

LUAD, UCEC, and SKCM are the cancer types where CYTIP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.004	0.835	<.001	27	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	OS	Median	II,III,IV	1.000	0.315	.026	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CYTIP–LUAD (OS)

Open the LUAD breakdown →