CYTIP

Across TCGA pan-cancer cohorts, CYTIP RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of CYTIP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CYTIP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CYTIP is over-expressed in tumor, although a few such as LUSC and COAD show the opposite, repressed pattern.

KIRC, LUSC, and COAD are the cancer types where CYTIP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CYTIP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+1.592	<.001	11	view →
LUSC	Male	II,III,IV	−1.642	<.001	8	view →
COAD	Female	All	−0.868	<.001	6	view →
HNSC	Female	All	+0.694	.034	3	view →
LUAD	All	II,III,IV	−0.545	.008	3	view →
KICH	All	All	+1.086	.012	2	view →
LIHC	Male	All	−0.851	<.001	2	view →
THCA	Female	All	−0.669	.046	1	view →
BRCA	All	All	+0.267	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

CYTIP–KIRC

Open the KIRC breakdown →