CYTIP

Across TCGA cell cohorts, CYTIP RNA expression is significantly associated with the go_rna of many other GO terms, with 2,185 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CYTIP-associated GO terms across cancer lineages are Regulation of CD4-positive, alpha-beta T cell activation, Toll-like receptor 3 signaling pathway, and Synaptic vesicle recycling. Each is linked with CYTIP in more than 5 cancer types. Because this analysis shows association rather than direction, both CYTIP-to-partner and partner-to-CYTIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of CD4-positive, alpha-beta T cell activation grouped by CYTIP-low versus CYTIP-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYTIP→partner) and Y-score (partner→CYTIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of CD4-positive, alpha-beta T cell activation →	+0.077	+0.448	.001	.004	2	6
BLOOD_Leukemia	Toll-like receptor 3 signaling pathway →	+0.061	+1.251	<.001	<.001	3	5
BLOOD_Leukemia	Synaptic vesicle recycling →	+0.058	+1.810	.004	<.001	3	5
LARGE_INTESTINE	Blastocyst growth →	-0.138	-0.847	<.001	.007	2	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.143	+0.150	<.001	.003	3	4
BLOOD_Myeloma	Regulation of triglyceride catabolic process →	-0.118	-0.808	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,185 associations by consensus.

Regulation of CD4-positive, alpha-beta T cell activation by CYTIP expression — KIDNEY

Explore this box plot interactively →