CYTIP

Across TCGA cell cohorts, CYTIP mutation is significantly associated with the mutation status of many other genes, with 3,215 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CYTIP-associated genes across cancer lineages are INTS2, ZNF835, and PITPNM2. Each is linked with CYTIP in more than 3 cancer types. Because this analysis shows association rather than direction, both CYTIP-to-partner and partner-to-CYTIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INTS2 grouped by CYTIP-low versus CYTIP-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYTIP→partner) and Y-score (partner→CYTIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	INTS2 →	+4.560	+4.870	<.001	<.001	1	4
UPPER_AERODIGESTIVE_TRACT	ZNF835 →	+3.954	+4.906	.001	.001	1	4
BLOOD_Leukemia	PITPNM2 →	+2.975	+4.741	<.001	<.001	1	4
SKIN	RBM6 →	+3.321	+3.035	.008	.008	1	3
BLOOD_Leukemia	EEF1A2 →	+4.560	+4.309	.007	.007	1	3
BLOOD_Leukemia	PCDH11X →	+3.823	+4.430	.001	.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,215 associations by consensus.

INTS2 by CYTIP expression — BLOOD_Leukemia

Explore this box plot interactively →