CYTIP

Across TCGA cell cohorts, CYTIP mutation is significantly associated with the drug of many other genes, with 44 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CYTIP-associated genes across cancer lineages are IAP_5620, Leflunomide, and ULK1_4989. Each is linked with CYTIP in more than 1 cancer types. Because this analysis shows association rather than direction, both CYTIP-to-partner and partner-to-CYTIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IAP_5620 grouped by CYTIP-low versus CYTIP-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYTIP→partner) and Y-score (partner→CYTIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IAP_5620 →	+0.361	+2.871	.039	.021	3	1
LARGE_INTESTINE	Leflunomide →	+0.258	+2.991	.033	.018	3	1
LARGE_INTESTINE	ULK1_4989 →	+0.739	+2.871	.017	.021	3	1
LARGE_INTESTINE	LMP744 →	+0.717	+2.871	.025	.021	3	1
LARGE_INTESTINE	WZ3105 →	+0.720	+2.874	.028	.021	3	1
LARGE_INTESTINE	PHA-793887 →	+0.774	+2.874	.025	.021	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

IAP_5620 by CYTIP expression — LARGE_INTESTINE

Explore this box plot interactively →