CYSLTR1

Across TCGA cell cohorts, CYSLTR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,725 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CYSLTR1-associated GO terms across cancer lineages are Negative regulation of mast cell degranulation, Regulation of mRNA processing, and Negative regulation of regulatory T cell differentiation. Each is linked with CYSLTR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CYSLTR1-to-partner and partner-to-CYSLTR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mast cell degranulation grouped by CYSLTR1-low versus CYSLTR1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYSLTR1→partner) and Y-score (partner→CYSLTR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Negative regulation of mast cell degranulation →	+1.480	+2.660	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA processing →	+0.071	+0.045	.004	.007	3	5
BLOOD_Myeloma	Negative regulation of regulatory T cell differentiation →	+0.121	+2.441	<.001	<.001	3	5
BLOOD_Lymphoma	Response to molecule of fungal origin →	+1.366	+0.862	<.001	<.001	3	5
BLOOD_Lymphoma	Fc-epsilon receptor signaling pathway →	+0.085	+1.075	<.001	<.001	3	5
BLOOD_Lymphoma	Cellular response to molecule of fungal origin →	+1.366	+0.862	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,725 associations by consensus.

Negative regulation of mast cell degranulation by CYSLTR1 expression — BLOOD_Myeloma

Explore this box plot interactively →