Across TCGA patient cohorts, CYS1 mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYS1-associated genes across cancer lineages are MIR7702, RN7SL711P, and DNAJB8-AS1. Each is linked with CYS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYS1-to-partner and partner-to-CYS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYS1→partner) and Y-score (partner→CYS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7702 →	+0.757	+6.475	<.001	<.001	3	1
UCEC	RN7SL711P →	+0.418	+4.113	.001	.005	3	1
SKCM	DNAJB8-AS1 →	+0.030	+5.224	<.001	.007	3	1
SKCM	RN7SL398P →	+0.221	+5.970	<.001	.002	3	1
COAD	RNU6-929P →	+0.368	+7.741	<.001	.009	3	1
UCEC	MIR302C →	+1.231	+4.813	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

Exploration

CYS1 survival (RNA) · tumor vs normal (RNA) · all CYS1 data types