CYRIB

Across TCGA patient cohorts, CYRIB RNA expression is significantly associated with the protein abundance of many other proteins, with 12,222 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CYRIB-associated proteins across cancer lineages are AGO1, STK10, and OTUD6B. Each is linked with CYRIB in more than 6 cancer types. Because this analysis shows association rather than direction, both CYRIB-to-partner and partner-to-CYRIB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYRIB versus AGO1 in BRCA, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYRIB→partner) and Y-score (partner→CYRIB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AGO1 →	-0.276	-0.682	<.001	<.001	3	7
GBM	STK10 →	+0.339	+0.451	<.001	<.001	3	6
OV	OTUD6B →	+0.472	+0.587	<.001	.002	3	6
BRCA	ALG13 →	-0.299	-0.439	.003	.004	3	6
GBM	HCK →	+0.578	+0.487	<.001	<.001	3	5
GBM	HK3 →	+0.660	+0.335	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,222 associations by consensus.

CYRIB vs AGO1 — BRCA

Explore this scatter interactively →