CYRIB

Across TCGA cell cohorts, CYRIB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,340 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CYRIB-associated GO terms across cancer lineages are Protein localization to condensed chromosome, Protein localization to kinetochore, and Positive regulation of cell cycle process. Each is linked with CYRIB in more than 12 cancer types. Because this analysis shows association rather than direction, both CYRIB-to-partner and partner-to-CYRIB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to condensed chromosome grouped by CYRIB-low versus CYRIB-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYRIB→partner) and Y-score (partner→CYRIB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to condensed chromosome →	+0.196	+1.093	<.001	.001	3	13
BLOOD_Myeloma	Protein localization to kinetochore →	+0.146	+1.195	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle process →	+0.087	+0.940	.001	.001	3	12
SOFT_TISSUE	DNA-templated DNA replication →	+0.124	+0.878	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitotic cell cycle phase transition →	+0.117	+0.857	<.001	.002	3	12
BLOOD_Lymphoma	Regulation of mitotic sister chromatid separation →	+0.117	+1.136	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,340 associations by consensus.

Protein localization to condensed chromosome by CYRIB expression — OESOPHAGUS

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