CYRIA

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CYRIA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,621 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CYRIA-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Protein stabilization, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with CYRIA in more than 9 cancer types. Because this analysis shows association rather than direction, both CYRIA-to-partner and partner-to-CYRIA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYRIA→partner) and Y-score (partner→CYRIA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHNegative regulation of myoblast fusion →+0.122+0.887<.001.001310
STOMACHProtein stabilization →+0.071+1.227<.001<.001310
STOMACHNegative regulation of syncytium formation by plasma membrane fusion →+0.119+0.888<.001.001310
STOMACHRegulation of syncytium formation by plasma membrane fusion →+0.114+1.085<.001.004310
STOMACHRegulation of myoblast fusion →+0.109+1.142<.001.00239
STOMACHProcess utilizing autophagic mechanism →+0.073+1.424.002.00239
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,621 associations by consensus.

Exploration