CYP8B1

Across TCGA patient cohorts, CYP8B1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,436 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CYP8B1-associated proteins across cancer lineages are UBTF_S484, URB1, and URB2. Each is linked with CYP8B1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CYP8B1-to-partner and partner-to-CYP8B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP8B1 versus UBTF_S484 in GBM, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP8B1→partner) and Y-score (partner→CYP8B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	UBTF_S484 →	-0.782	-0.137	<.001	<.001	3	3
LSCC	URB1 →	-0.274	-0.259	.001	.001	3	3
BRCA	URB2 →	-0.297	-0.234	<.001	.001	1	5
LSCC	RANBP2 →	-0.173	-0.237	.002	.001	3	3
BRCA	ATAD2 →	-0.566	-0.308	<.001	.001	3	3
BRCA	BRIP1_T989 →	-0.699	-0.289	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,436 associations by consensus.

CYP8B1 vs UBTF_S484 — GBM

Explore this scatter interactively →