Across TCGA patient cohorts, CYP51A1-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,846 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYP51A1-AS1-associated proteins across cancer lineages are SDF2L1, GMPPA, and PCGF2. Each is linked with CYP51A1-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYP51A1-AS1-to-partner and partner-to-CYP51A1-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP51A1-AS1→partner) and Y-score (partner→CYP51A1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SDF2L1 →	-0.381	-0.170	<.001	.005	3	4
LSCC	GMPPA →	-0.299	-0.146	<.001	<.001	3	4
LSCC	PCGF2 →	+0.348	+0.173	<.001	<.001	3	4
LSCC	PLCG2 →	-0.450	-0.146	<.001	<.001	3	3
GBM	PPIB →	-0.429	-0.323	<.001	<.001	3	3
LSCC	PRAM1 →	-0.431	-0.136	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,846 associations by consensus.

Exploration

CYP51A1-AS1 survival (RNA) · tumor vs normal (RNA) · all CYP51A1-AS1 data types