CYP4Z2P

Across TCGA patient cohorts, CYP4Z2P mutation is significantly associated with the RNA expression of many other genes, with 2,415 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP4Z2P-associated genes across cancer lineages are VEZF1P1, EIF1AXP1, and RPL23AP7. Each is linked with CYP4Z2P in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP4Z2P-to-partner and partner-to-CYP4Z2P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VEZF1P1 grouped by CYP4Z2P-low versus CYP4Z2P-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4Z2P→partner) and Y-score (partner→CYP4Z2P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	VEZF1P1 →	+0.031	+1.570	.002	.005	3	2
SKCM	EIF1AXP1 →	+0.380	+2.341	.008	.003	3	2
SKCM	RPL23AP7 →	+0.371	+2.897	.007	.001	3	2
SKCM	AK2P2 →	+0.137	+1.919	<.001	.001	3	2
LGG	LINC01861 →	+0.093	+4.987	<.001	.009	3	2
UCEC	POLRMTP1 →	+0.400	+2.010	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,415 associations by consensus.

VEZF1P1 by CYP4Z2P expression — SKCM

Explore this box plot interactively →