Across TCGA cell cohorts, CYP4X1 mutation is significantly associated with the mutation status of many other genes, with 1,349 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CYP4X1-associated genes across cancer lineages are RBM10, SIPA1L3, and MID2. Each is linked with CYP4X1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYP4X1-to-partner and partner-to-CYP4X1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4X1→partner) and Y-score (partner→CYP4X1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RBM10 →	+3.532	+3.357	.005	.005	1	4
CNS	SIPA1L3 →	+4.862	+4.862	<.001	<.001	1	4
SKIN	MID2 →	+5.117	+3.977	.001	.001	1	3
LUNG_NSCLC_LUAD	ZNF239 →	+4.772	+5.339	.004	.004	1	3
LARGE_INTESTINE	TOX4 →	+2.865	+4.217	.007	.007	1	3
SKIN	UNC13B →	+2.725	+3.222	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,349 associations by consensus.

Exploration

CYP4X1 survival (RNA) · tumor vs normal (RNA) · all CYP4X1 data types