Across TCGA patient cohorts, CYP4F8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,461 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CYP4F8-associated GO terms across cancer lineages are Proton motive force-driven ATP synthesis, Positive regulation of DNA repair, and Protein stabilization. Each is linked with CYP4F8 in more than 9 cancer types. Because this analysis shows association rather than direction, both CYP4F8-to-partner and partner-to-CYP4F8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F8→partner) and Y-score (partner→CYP4F8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Proton motive force-driven ATP synthesis →	+0.048	+0.071	.008	.004	1	10
KIRC	Positive regulation of DNA repair →	+0.022	+0.020	<.001	.004	2	9
UCEC	Protein stabilization →	+0.018	+0.063	<.001	.001	3	8
STAD	Aerobic respiration →	+0.061	+0.085	<.001	.005	1	10
UCEC	Mitochondrial gene expression →	+0.026	+0.087	<.001	.003	2	9
KIRC	Regulation of mitochondrial translation →	+0.034	+0.014	<.001	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,461 associations by consensus.

Exploration

CYP4F8 survival (RNA) · tumor vs normal (RNA) · all CYP4F8 data types