Across TCGA patient cohorts, CYP4F8 mutation is significantly associated with the RNA expression of many other genes, with 3,603 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP4F8-associated genes across cancer lineages are MTA2, TEX30, and RBBP8. Each is linked with CYP4F8 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYP4F8-to-partner and partner-to-CYP4F8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F8→partner) and Y-score (partner→CYP4F8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTA2 →	+0.341	+2.265	.003	.005	3	4
UCEC	TEX30 →	+0.519	+2.233	.003	.005	3	4
SKCM	RBBP8 →	+0.670	+1.784	<.001	.007	3	3
UCEC	OIP5 →	+0.820	+2.158	<.001	<.001	3	3
UCEC	TIMM44 →	+0.409	+3.042	<.001	<.001	3	3
UCEC	CACTIN →	+0.497	+2.148	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,603 associations by consensus.

Exploration

CYP4F8 survival (RNA) · tumor vs normal (RNA) · all CYP4F8 data types