Across TCGA patient cohorts, CYP4F30P mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP4F30P-associated genes across cancer lineages are RN7SKP60, RNA5SP414, and RN7SL248P. Each is linked with CYP4F30P in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP4F30P-to-partner and partner-to-CYP4F30P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F30P→partner) and Y-score (partner→CYP4F30P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP60 →	+0.351	+5.520	<.001	<.001	3	2
BRCA	RNA5SP414 →	+0.317	+7.471	<.001	.008	3	1
UCEC	RN7SL248P →	+0.212	+5.722	<.001	.001	3	1
BRCA	RNU4-77P →	+0.132	+7.471	<.001	.008	3	1
BRCA	RNA5SP416 →	+0.482	+7.471	<.001	.008	3	1
BRCA	AKR1B1P5 →	+0.055	+5.441	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

CYP4F30P survival (RNA) · tumor vs normal (RNA) · all CYP4F30P data types