Across TCGA cell cohorts, CYP4F3 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CYP4F3-associated genes across cancer lineages are GRM6, DBX2, and SAMD7. Each is linked with CYP4F3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP4F3-to-partner and partner-to-CYP4F3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F3→partner) and Y-score (partner→CYP4F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GRM6 →	+0.062	+3.378	.001	.001	3	1
LARGE_INTESTINE	DBX2 →	+0.009	+3.240	<.001	.004	3	1
LARGE_INTESTINE	SAMD7 →	+0.015	+3.141	.001	.002	3	1
LARGE_INTESTINE	COL25A1 →	+0.041	+3.392	.002	.001	3	1
LARGE_INTESTINE	OR2J3 →	+0.032	+2.657	<.001	.007	3	1
LARGE_INTESTINE	FAM205A →	+0.018	+3.029	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration

CYP4F3 survival (RNA) · tumor vs normal (RNA) · all CYP4F3 data types