Across TCGA patient cohorts, CYP4F2 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP4F2-associated genes across cancer lineages are p27_pT157, p90 RSK, and Bad_pS112. Each is linked with CYP4F2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP4F2-to-partner and partner-to-CYP4F2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F2→partner) and Y-score (partner→CYP4F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	p27_pT157 →	+0.173	+2.321	<.001	.001	3	2
SKCM	p90 RSK →	+0.188	+3.169	.012	.017	3	2
SKCM	Bad_pS112 →	+0.201	+1.597	.002	.040	3	2
SKCM	BRCA2 →	-0.150	-2.977	.029	.032	3	2
UCEC	INPP4B →	-0.280	-1.807	.006	.024	3	2
UCEC	Notch1 →	+0.139	+1.691	.001	.011	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Exploration

CYP4F2 survival (RNA) · tumor vs normal (RNA) · all CYP4F2 data types