Across TCGA patient cohorts, CYP4F12 mutation is significantly associated with the RNA expression of many other genes, with 1,512 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP4F12-associated genes across cancer lineages are LRRC30, TIMM44, and DPM2. Each is linked with CYP4F12 in more than 2 cancer types. Because this analysis shows association rather than direction, both CYP4F12-to-partner and partner-to-CYP4F12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F12→partner) and Y-score (partner→CYP4F12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	LRRC30 →	+0.026	+4.314	.005	.009	3	3
UCEC	TIMM44 →	+0.263	+2.042	.004	.004	3	3
UCEC	DPM2 →	+0.271	+2.330	.003	<.001	3	3
PRAD	H2ACP1 →	+0.209	+7.939	<.001	.008	3	2
PRAD	OR4C14P →	+0.174	+7.939	<.001	.008	3	2
UCEC	SNED1 →	-0.414	-1.791	.006	.004	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,512 associations by consensus.

Exploration

CYP4F12 survival (RNA) · tumor vs normal (RNA) · all CYP4F12 data types