Across TCGA patient cohorts, CYP4F12 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYP4F12-associated genes across cancer lineages are INPP4B, VHL, and Caspase-8. Each is linked with CYP4F12 in more than 2 cancer types. Because this analysis shows association rather than direction, both CYP4F12-to-partner and partner-to-CYP4F12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F12→partner) and Y-score (partner→CYP4F12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.250	-1.440	.012	.022	3	3
UCEC	VHL →	-0.702	-2.485	<.001	<.001	3	3
SKCM	Caspase-8 →	-0.126	-1.381	.004	.038	3	3
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.450	+2.584	.004	.010	3	2
UCEC	Rab11 →	-0.092	-1.201	.040	.028	3	2
UCEC	XBP1 →	-0.169	-2.057	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

CYP4F12 survival (RNA) · tumor vs normal (RNA) · all CYP4F12 data types