Across TCGA cell cohorts, CYP4F12 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CYP4F12-associated genes across cancer lineages are TBC1D21, PFN3, and PYDC2. Each is linked with CYP4F12 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP4F12-to-partner and partner-to-CYP4F12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4F12→partner) and Y-score (partner→CYP4F12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBC1D21 →	+0.015	+5.022	<.001	.002	3	1
LARGE_INTESTINE	PFN3 →	+0.169	+4.467	<.001	.004	3	1
LARGE_INTESTINE	PYDC2 →	+0.108	+4.415	<.001	.007	3	1
BREAST	TEX43 →	+0.120	+4.672	<.001	.002	3	1
BLOOD_Lymphoma	ATP6V1G3 →	+0.229	+3.584	.002	.004	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

CYP4F12 survival (RNA) · tumor vs normal (RNA) · all CYP4F12 data types