CYP4F10P

Across TCGA pan-cancer cohorts, CYP4F10P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated CYP4F10P data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher CYP4F10P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CYP4F10P expression acts as an unfavorable survival marker, although some lineages such as LIHC show a favorable association.

CHOL, KICH, and THYM are the cancer types where CYP4F10P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	DFS	Tertile	II,III,IV	0.030	0.430	<.001	99	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
THYM	DFS	Tertile	All	0.130	0.773	<.001	66	view →
BRCA	DFS	Tertile	III,IV	0.277	0.801	<.001	60	view →
STAD	OS	Quartile	All	0.298	0.588	.004	41	view →
SKCM	OS	Tertile	III,IV	0.232	0.721	.010	18	view →
READ	DFS	Tertile	IV	0.027	0.636	<.001	18	view →
KIRC	OS	Tertile	All	0.501	0.644	.025	12	view →
PAAD	DFS	Tertile	II,III,IV	0.182	0.484	.002	9	view →
COAD	DFS	Tertile	IV	0.028	0.496	<.001	9	view →
LUAD	OS	Tertile	All	0.518	0.689	.039	6	view →
UCEC	OS	Tertile	All	0.873	0.931	.027	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

CYP4F10P–CHOL (DFS)

Open the CHOL breakdown →