CYP4B1

Across TCGA patient cohorts, CYP4B1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,101 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYP4B1-associated genes across cancer lineages are MRGBP, GALNT16, and PDE8B. Each is linked with CYP4B1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CYP4B1-to-partner and partner-to-CYP4B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP4B1 versus MRGBP in HNSC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP4B1→partner) and Y-score (partner→CYP4B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MRGBP →	-1.800	-0.766	.004	.007	3	3
BRCA	GALNT16 →	+2.265	+0.980	<.001	.004	3	2
BRCA	PDE8B →	+0.776	+0.921	<.001	.006	3	2
BRCA	TCEAL4 →	+1.049	+0.970	.002	.002	3	2
BRCA	PDE5A →	+1.575	+0.660	.003	.006	3	2
BRCA	EFNA3 →	-1.877	-0.561	.004	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,101 associations by consensus.

CYP4B1 vs MRGBP — HNSC

Explore this scatter interactively →