CYP3A52P

Across TCGA pan-cancer cohorts, CYP3A52P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated CYP3A52P data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CYP3A52P RNA is associated with better overall survival. In most high-consensus cancer types, elevated CYP3A52P expression acts as an unfavorable survival marker, although some lineages such as LUAD and ESCA show a favorable association.

LUAD, ESCA, and BLCA are the cancer types where CYP3A52P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	0.762	0.509	.001	71	view →
ESCA	DFS	Quartile	III,IV	0.523	0.245	.015	45	view →
BLCA	OS	Tertile	II,III,IV	0.685	0.398	.009	42	view →
PAAD	OS	Tertile	All	0.623	0.270	.014	30	view →
UCS	DFS	Tertile	III,IV	0.874	0.347	.022	24	view →
CESC	OS	Tertile	II,III,IV	1.000	0.726	.038	12	view →
THCA	DFS	Tertile	IV	0.630	0.961	.017	12	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
CHOL	DFS	Tertile	II,III,IV	0.114	0.502	.048	9	view →
LGG	DFS	Tertile	All	0.742	0.861	.005	8	view →
THYM	OS	Quartile	All	0.570	0.932	.017	6	view →
MESO	OS	Tertile	IV	0.700	0.281	.030	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

CYP3A52P–LUAD (OS)

Open the LUAD breakdown →