CYP3A43

Across TCGA patient cohorts, CYP3A43 protein abundance is significantly associated with the protein abundance of many other proteins, with 188 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CYP3A43-associated proteins across cancer lineages are RNF141, CPEB4, and LRMDA_S153. Each is linked with CYP3A43 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP3A43-to-partner and partner-to-CYP3A43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP3A43 versus RNF141 in BRCA, with a Pearson correlation of 0.96.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP3A43→partner) and Y-score (partner→CYP3A43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNF141 →	+0.693	+2.615	<.001	.001	3	1
BRCA	CPEB4 →	+0.652	+2.615	<.001	.001	3	1
BRCA	LRMDA_S153 →	-2.046	-3.403	<.001	.001	3	1
BRCA	ABRAXAS1_S386 →	+1.381	+3.710	.003	.001	2	1
BRCA	ARFGEF2 →	+0.409	+2.615	<.001	.001	2	1
BRCA	ARHGAP31_S387 →	-0.793	-3.403	<.001	.001	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 188 associations by consensus.

CYP3A43 vs RNF141 — BRCA

Explore this scatter interactively →