CYP2W1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CYP2W1 protein abundance is significantly associated with the RNA expression of many other genes, with 901 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CYP2W1-associated genes across cancer lineages are RTP4, TRGC1, and SALL4. Each is linked with CYP2W1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP2W1-to-partner and partner-to-CYP2W1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP2W1 versus RTP4 in HNSC, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2W1→partner) and Y-score (partner→CYP2W1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRTP4 →-2.258-1.224<.001.00432
HNSCTRGC1 →-1.086-1.333.006.00432
HNSCSALL4 →+1.194+1.249.006<.00131
HNSCCD40LG →-1.194-1.228.005.00131
HNSCURI1 →+0.413+1.226.002.00931
HNSCSIGLEC6 →-0.628-1.179.007.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 901 associations by consensus.

CYP2W1 vs RTP4 — HNSC

Per-sample scatter of CYP2W1 vs RTP4 in HNSC (Pearson r = -0.54).

Explore this scatter interactively →

Exploration