CYP2U1

Across TCGA cell cohorts, CYP2U1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,507 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CYP2U1-associated GO terms across cancer lineages are Cell division, DNA damage tolerance, and Regulation of smoothened signaling pathway. Each is linked with CYP2U1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CYP2U1-to-partner and partner-to-CYP2U1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell division grouped by CYP2U1-low versus CYP2U1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2U1→partner) and Y-score (partner→CYP2U1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Cell division →	+0.084	+0.863	<.001	<.001	3	12
PANCREAS	DNA damage tolerance →	+0.080	+0.927	.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of smoothened signaling pathway →	+0.064	+1.272	<.001	.001	3	11
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.163	+1.270	.002	.001	3	10
OESOPHAGUS	Golgi vesicle transport →	+0.066	+1.008	.009	.003	2	11
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.125	+1.383	.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,507 associations by consensus.

Cell division by CYP2U1 expression — OVARY

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